All you need to Know About HLA-B27 Test

HLA B27 is a test that is conducted to identity the Human Leukocyte antigen (HLA B27) protein. This protein is situated on the white blood cells surface and is an antigen that helps the immune system infection causing aliens and healthy body tissues.

Though most of the HLAs protect the body against harmful invaders, HLA B27 is on particular protein that is responsible for system dysfunction by attacking the healthy cells instead of foreign substances. This causes autoimmune diseases like ankylosing spondylitis or rheumatoid arthritis.

HLA-B27 Test

Symptoms that indicate Test Taking
HLA-B27 test is taken alongside other tests like MRI scan, urine and blood tests to confirm about the presence of autoimmune disease.

  • Joint inflammation and skin lesions
  • Pain in the joints
  • Eye inflammation that reoccurs
  • Swelling or stiffness in the neck, chest or spine

Auto-immune conditions due to HLA-B27
Based on the symptoms the doctor may advice the test to check for the presence and progression of HLA-B27 with certain autoimmune conditions like

  • Bone inflammation in the spine – Ankylosing spondylitis
  • Joint inflammation in joints, eyes, urethra and skins lesions at times – Reactive arthritis
  • Swelling and irritation at eyes middle layer – Anterior uveitis
  • Joint stiffness, pain, redness, limping, swelling and reduced motion range – Juvenile rheumatoid arthritis

Besides, HLA antigen tests are also taken when a patient needs to undergo a transplant of kidney or bone marrow as they help in determining a suitable match of donor.

Diagnosis
If the test is positive, it indicates the presence HLA- B27 in blood. Though, it still is not a cent percent confirmation that an autoimmune condition may develop. Other symptoms are also taken into account including blood tests and diagnostic exams.

Conclusion
HLA-B27 indicates the presence of the protein in blood but a positive or negative result cannot be taken as a cent percent confirmation of the autoimmune disorder. Once the test is done and results are out, the doctor will advise you on further steps around the possible condition.

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All you Need to know about Brain Tumor

A brain tumor is a condition that is caused when abnormal cells in the brain grow within the brain or the spinal cord. It can be life threatening because it can disrupt brain functioning. There are two types of brain tumors, ones that are benign (cancerous) and the other malignant (malignant). The life expectancy varies depending upon the stage of the cancer.

Benign Tumor – This tumor grows slowly and does not spread to other tissues, thus is not cancerous in nature.

Malignant Tumor – This tumor grows very fast and contains cancerous cells that invade other parts of the brain and is considered to be life-threatening condition.

Brain Tumors are also classified as primary and secondary tumors depending on their origin. If the tumor starts in the brain it is known as primary tumor and if it originates from some other part of the body, it is known as a secondary or metastatic tumor.

Brain Tumor - signs

Symptoms

The symptoms of a brain tumor depend upon the type of tumor and the origin of it. The symptoms are mild initially and gradually increase. Sometimes there may be no symptoms at all. Some common symptoms –

A headache that persists
Nausea, vomiting, and drowsiness
Speech issues
Memory Issues
Seizures or convulsions
Personality Change                                                                                                                                              Coordination Change

Diagnosis
Diagnosis involves various tests to be carried out including the following-

EEG – An electroencephalogram is used to record brain activities for abnormalities if any using electrodes that are attached to the head.

CT Scan – It gives a detailed X ray picture of the patient’s brain

MRI Scan – It makes use of magnetic field as well as radio waves and provides a detailed image of the brain
Even biopsy is used to further confirm the presence of a tumor.

Treatment
The treatment depends on the diagnosis. It includes factors like the type of tumor, the age of the patient, size of the tumor, tolerance levels of the patient to name a few.

Surgery – The first course of treatment for Cancer starts with surgery and removal of the tumor or a part of it as much as possible. Due care is taken to avoid any harm to the neighboring tissues. The remaining tumor is removed with the help of various cancer therapies.

Chemotherapy – Chemotherapy is used for treating a serious type of malignant tumor. It stops the cells from multiplying or duplicating.

Radiation Therapy – Radiotherapy uses intense energy beams to destroy the tumor and prevent it from growing. It attacks the tumor cells, leading to shrinkage in the tumor, which can further be managed using an immune system of a person.

Radio Surgery – Also known as stereotactic radiosurgery (SRS), this treatment involves giving a targeted and precise dose in the form of an X-ray radiation.

Risk Factors – There is no definite reason behind brain tumors. It might be hereditary but in rare cases. The only risk factor associated with the brain tumor is radiation exposure.

Survival – The survival rate post the diagnosis also depends on a lot of factors but for malignant tumors of a primary type, the 5-year survival rate is even less than 35%.

RRMCH is one the best hospitals in Bangalore and amongst the best Neuro hospitals in India. Equipped with the latest in Medical Technology, it also offers the expertise of the best neurologist in Bangalore.

HOW TO PREVENT BONE INJURY?

As we age our bones start becoming in brittle as they tend to lose their bone density. The risk of injuries increases and hence it becomes important that we pay attention to our bone health and stay away from orthopaedic injuries.
Throughout the aging process of the body, there is bone loss and old bones are absorbed with the creation of the new bone. The bone health depends on apparently the balance between the old and the new bones. Bone loss also happens across your lifespan when the body absorbs calcium and phosphate in high quantity from the bones.
Hence, you need to be aware and work on keeping your bones strong enough. Here are a few tips you can use to keep your bones healthy throughout and decrease if not stop the rapid weakening of the bones.

bones_with_no_personal_injury

Avoid Addictions – Smoking and alcohol can affect your bone health hence avoid smoking as far as possible and keep your alcohol habits at bay.

Balance your Diet – as they say you are what you eat, so keep yourself fit by eating a balanced diet and avoiding junk. Add a bit of walking, jogging or exercise to your daily routine. This will certainly make you fitter and enhance your bone health too.

Vitamin D Profile Check – Many women after pregnancy tend to lose vitamin D from the body. As Vitamin D is required for absorbing calcium also, its an essential component as calcium is bone food. So, getting Vitamin D profile checked is advisable and if low, vitamin D supplement intake is required.

Heath Check – A routine health check is important so as to know how your body and bones are doing. So meet up your physician and if required get your tests done to check your body and bone health. Based on the findings the doctor will recommend you further action.

Well, small inclusions and exclusions in your daily lifestyle can go a long way in maintaining your bone health and reducing bone injuries or spine injuries and keep you independent and strong.

 

RRMCH has got the best team of orthopaedic doctors in Bangalore. RRMCH has got many reviews as best orthopedic hospital in Bangalore by treating all kinds of RTA

Health Tips For Women Above 40

As women age and surpass the middle age milestone called 40, even though age is just a number, practically the body does have to deal with certain issues that crop up as we enter this phase. So what can you do to keep your health in optimal condition? Here are few tips that might just help you out.

Health First – Many a times while keeping the family needs as a priority women forget to check on their health issues or ignore It most of the times. One needs to understand that only when one is healthy then only can they take care of their loved ones.

Health Tips For Women Above 40

Body Check – If you haven’t done a medical checkup its time. Once you hit 40 do it once every two to three years. Check for deficiencies in your body particularly Calcium, Vitamin D and B12. Vitamin D and Calcium are needed for strong bones and in your 40’s you require 1000mg of calcium and 400 to 800 UI of vitamin D every single day so either you have to switch to that sort of diet or go for supplements. The checks you need at this age include eye testing, BP test, Mole check, Mammogram, Glucose test Pap and pelvic test as well as thyroid. All these need to be done every 2 – 3 years approximately.

Exercise – Exercise is good for all but more so once you turn 40. You are aging and you need to exercise to stay fit. Kick start your day with strength training and see the change within 6 months. Just dedicate 30 minutes a day to it.

Diet Check – It’s time you revamp your diet and go for a balanced one which will help you cope with your deficiencies and keep your cholesterol levels under check. Having breakfast daily can help greatly against skipping it. A study reveals that over a period of time people who take good breakfast lose more weight than the ones who make breakfast their smallest meal. Get in a lot of protein as they are mood boosters and help you relieve yourself from poor memory, excessive thinking or depression.

Get good Sleep – Sleeping helps you reduce stress and hence a good sleep is important. Particularly women don’t care about it much and it ultimately takes a toll on their health. Also try to control your stress through meditation and yoga. This will help you stay fit physically and mentally.

Spend time with Girl Friends – Ya, you might be busy to the core but take out time to hangout with your girl buddies because it is found that women with socialization or hobby activities have less risk of heart disease or less blood pressure and diabetes issues.

RRMCH has got the best health checkup packages in Bangalore. You can check out the pricing packages of 4 plans available for all employees and individuals.

Post Stroke Motor Skill Recovery Made Faster – Vagus Nerve Stimulation methodology

When a person suffers from a stroke, the nerve cells in the brain die away due to blockage in supply of blood. This results in failure in motor skills because the nerves are dead and the connection between the brain and the nerves is lost. The methods that are in use bypass the damaged area of the brain and use other brain cells to handle the lost function. As there are less number of neurons to spare, the patient has to face a movement disability that is long lasting. Now, researchers at the university of Texas, Dallas have found a way out to speed up the motor skill recovery process with the help of the vagus nerve stimulation methodology.

vagus-vagal-nerve-stimulation

The Vagus nerve is responsible for controlling the parasympathetic nervous system which in turn supervises numerous bodily functions like circulation and digestion. A device is implanted in the neck to achieve electrical stimulation. VSN, has been already used for treating depression and is a well- documented technique for fine tuning the functioning of the brain. The role of the VNS is to strengthen the path that leads to the neurons that is damaged after stroke. There has been a visible increase of three fold to five fold in the engaged neuron with VNS addition to the rehab.

The study determines that if we use the approach to deal with complicated motor skills, these improvements further improve the simple movements. It is a significant step in creating guidelines for using VS for post stroke therapy as per the researchers.

The results of the preclinical study carried out by the scientists here showed that the recovery in rodents on which the vagus stimulation (VNS) couple with physical therapy experiment was carried out, doubled long term recovery rate as compared to the therapy in use in these times.

The work is already published in the journal Stroke, and the trial is already on in humans in Dallas and 15 other sites in the country. The researchers have also developed an application that can help us monitor their performance and recovery process remotely too while they use it at home for improving their upper limb motor skills.

Rajarajeswari Heart Center, part of the esteem institute, Rajarajeswari Medical College and Hospital. Was established in May 2012 as an initial non-interventional department with 2D echocardiography, Treadmill Test and cardiac consultation.