All you need to Know About HLA-B27 Test

HLA B27 is a test that is conducted to identity the Human Leukocyte antigen (HLA B27) protein. This protein is situated on the white blood cells surface and is an antigen that helps the immune system infection causing aliens and healthy body tissues.

Though most of the HLAs protect the body against harmful invaders, HLA B27 is on particular protein that is responsible for system dysfunction by attacking the healthy cells instead of foreign substances. This causes autoimmune diseases like ankylosing spondylitis or rheumatoid arthritis.

HLA-B27 Test

Symptoms that indicate Test Taking
HLA-B27 test is taken alongside other tests like MRI scan, urine and blood tests to confirm about the presence of autoimmune disease.

  • Joint inflammation and skin lesions
  • Pain in the joints
  • Eye inflammation that reoccurs
  • Swelling or stiffness in the neck, chest or spine

Auto-immune conditions due to HLA-B27
Based on the symptoms the doctor may advice the test to check for the presence and progression of HLA-B27 with certain autoimmune conditions like

  • Bone inflammation in the spine – Ankylosing spondylitis
  • Joint inflammation in joints, eyes, urethra and skins lesions at times – Reactive arthritis
  • Swelling and irritation at eyes middle layer – Anterior uveitis
  • Joint stiffness, pain, redness, limping, swelling and reduced motion range – Juvenile rheumatoid arthritis

Besides, HLA antigen tests are also taken when a patient needs to undergo a transplant of kidney or bone marrow as they help in determining a suitable match of donor.

Diagnosis
If the test is positive, it indicates the presence HLA- B27 in blood. Though, it still is not a cent percent confirmation that an autoimmune condition may develop. Other symptoms are also taken into account including blood tests and diagnostic exams.

Conclusion
HLA-B27 indicates the presence of the protein in blood but a positive or negative result cannot be taken as a cent percent confirmation of the autoimmune disorder. Once the test is done and results are out, the doctor will advise you on further steps around the possible condition.

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Top 5 Pregnancy Complications To Be Aware Of

The news of pregnancy brings in smiles on the faces of the family members. On the flip side, during the three trimesters, you need to be on your toes and all alert because pregnancy can cause complications if proper care is not taken. Though you are going to be under the scanner all through the pregnancy cycle and your doctor is going to get you tested on various complications, you yourself need to be aware of them and take self-care to keep them at bay.

Here is a run through some complications of pregnancy that can be life threatening to the fetus and the mom as well.

Top 5 Pregnancy Complications To Be Aware Of

1. Pre-eclampisa – It is the almost rare condition in pregnancy because it usually affects only 5 % of the pregnant women in India. This condition is caused by high level of proteins in the urine, high blood pressure or kidney conditions post 20 weeks of pregnancy.
Care needs to be taken to be aware and act promptly by the doctor if there are even mild symptoms of it because it can progress fast and can be life-threatening to the baby and the mother too. The solution to it is early delivery.

2. Gestational Diabetes – This is one of the common conditions occurring in pregnant women in India. Around 10% women could be prey to this condition that can be diagnosed during 24-28 weeks of pregnancy. Post-diagnosis your blood sugar levels will be monitored on a regular basis. Most of them with mild conditions manage to keep it at bay through exercise and diet and are able to deliver healthy babies without complications. But, care needs to be taken to avoid it from aggravating because it can then cause serious harm to the fetus.

3. Placenta Previa – This condition can cause complications towards the end of pregnancy not in the early stages. Hence, the doctors check the location and placement of your placenta with a sonography test during the second     tri-semester. 1 in 200 women suffer from this condition and it can be quite dangerous if the placenta is at extremely low levels.

4. Miscarriage – One of the most dreaded conditions which can only be avoided by taking proper care, miscarriage is caused in the first 20 weeks. This is common with Indian women and 20% of them experience this condition within 12 weeks mostly. The symptoms of it include spotting and bleeding at the vagina. The doctor does a sonography to check for the condition.

5. Premature Delivery – Premature delivery is when the cervix opens before 37 weeks of pregnancy. If the delivery happens too early then it can be life-threatening for the baby, so care needs to be taken to avoid it.

The department of Obstetrics and Gynecology has been providing comprehensive health care for women. We provide regular clinical services in Obstetrics like antenatal care, labor management, postpartum Care. We also provide specialized care in high risk pregnancies like P.I.H, Eclampsia, GDM, Multiple gestations, BOH. With the backup of NICU, we are able to salvage preterm babies of 30 weeks on wards. Highly qualified doctors, with the help of well equipped labor ward, conduct normal and caesarian deliveries

HOW TO PREVENT BONE INJURY?

As we age our bones start becoming in brittle as they tend to lose their bone density. The risk of injuries increases and hence it becomes important that we pay attention to our bone health and stay away from orthopaedic injuries.
Throughout the aging process of the body, there is bone loss and old bones are absorbed with the creation of the new bone. The bone health depends on apparently the balance between the old and the new bones. Bone loss also happens across your lifespan when the body absorbs calcium and phosphate in high quantity from the bones.
Hence, you need to be aware and work on keeping your bones strong enough. Here are a few tips you can use to keep your bones healthy throughout and decrease if not stop the rapid weakening of the bones.

bones_with_no_personal_injury

Avoid Addictions – Smoking and alcohol can affect your bone health hence avoid smoking as far as possible and keep your alcohol habits at bay.

Balance your Diet – as they say you are what you eat, so keep yourself fit by eating a balanced diet and avoiding junk. Add a bit of walking, jogging or exercise to your daily routine. This will certainly make you fitter and enhance your bone health too.

Vitamin D Profile Check – Many women after pregnancy tend to lose vitamin D from the body. As Vitamin D is required for absorbing calcium also, its an essential component as calcium is bone food. So, getting Vitamin D profile checked is advisable and if low, vitamin D supplement intake is required.

Heath Check – A routine health check is important so as to know how your body and bones are doing. So meet up your physician and if required get your tests done to check your body and bone health. Based on the findings the doctor will recommend you further action.

Well, small inclusions and exclusions in your daily lifestyle can go a long way in maintaining your bone health and reducing bone injuries or spine injuries and keep you independent and strong.

 

RRMCH has got the best team of orthopaedic doctors in Bangalore. RRMCH has got many reviews as best orthopedic hospital in Bangalore by treating all kinds of RTA

Post Stroke Motor Skill Recovery Made Faster – Vagus Nerve Stimulation methodology

When a person suffers from a stroke, the nerve cells in the brain die away due to blockage in supply of blood. This results in failure in motor skills because the nerves are dead and the connection between the brain and the nerves is lost. The methods that are in use bypass the damaged area of the brain and use other brain cells to handle the lost function. As there are less number of neurons to spare, the patient has to face a movement disability that is long lasting. Now, researchers at the university of Texas, Dallas have found a way out to speed up the motor skill recovery process with the help of the vagus nerve stimulation methodology.

vagus-vagal-nerve-stimulation

The Vagus nerve is responsible for controlling the parasympathetic nervous system which in turn supervises numerous bodily functions like circulation and digestion. A device is implanted in the neck to achieve electrical stimulation. VSN, has been already used for treating depression and is a well- documented technique for fine tuning the functioning of the brain. The role of the VNS is to strengthen the path that leads to the neurons that is damaged after stroke. There has been a visible increase of three fold to five fold in the engaged neuron with VNS addition to the rehab.

The study determines that if we use the approach to deal with complicated motor skills, these improvements further improve the simple movements. It is a significant step in creating guidelines for using VS for post stroke therapy as per the researchers.

The results of the preclinical study carried out by the scientists here showed that the recovery in rodents on which the vagus stimulation (VNS) couple with physical therapy experiment was carried out, doubled long term recovery rate as compared to the therapy in use in these times.

The work is already published in the journal Stroke, and the trial is already on in humans in Dallas and 15 other sites in the country. The researchers have also developed an application that can help us monitor their performance and recovery process remotely too while they use it at home for improving their upper limb motor skills.

Rajarajeswari Heart Center, part of the esteem institute, Rajarajeswari Medical College and Hospital. Was established in May 2012 as an initial non-interventional department with 2D echocardiography, Treadmill Test and cardiac consultation.

Vitamin D Deficiency Signs Which You Tend to Ignore

Vitamin D is one of the most vital vitamins in the body and hence, its deficiency can affect the functioning of numerous systems across your body. It is made from cholesterol when your body is exposed to sunlight. More than a vitamin it is a hormone to which every cell in the body is receptive. While sunlight is a natural source, you can get it from foods like fatty fish and dairy products as well. As per the experts you cannot get the daily intake solely through food and relying on supplements is the way. Your daily intake of Vitamin D needs to be around 400-800 IU. Let us run down the causes, symptoms, diagnosis, treatment and risk factors associated with Vitamin D Deficiency.

Vitamin D Deficiency

Symptoms
The symptoms could mean different in different people. Here’s a run down –

Fatique or tiredness – If you are suffering from excessive fatigue or tiredness, you could have a Vitamin D deficiency. The doctor might suggest supplement intake to improve energy levels.

Pain in Bone / Back – Vitamin D is responsible for calcium absorption so bone or back pain could be a sign of inadequate levels of Vitamin D. Chronic back pain is a common example.

Depression – However strange it may sound, but yes depression could be a sign of Vitamin D deficiency. Vitamin D supplements can help improve moods as per research.

Hair Loss – Excessive hair loss can be caused to deficiency in Vitamin D. Many of us take it to be a result of stress and ignore but never does it strike that we get our Vitamin D tested.

Bone Loss – As vitamin D plays a significant role in bone metabolism management and absorption of calcium, a deficiency could lead to bone loss and increased risk of fractures.

Muscle Pain – Though not always, muscle pain could be a result of Vitamin D deficiency.

Diagnosis – You can find out if you have a Vitamin D deficiency of not by running a laboratory Vitamin D test. The reference levels for the test are as follows
Severe Deficiency  : < 10 ng/ml
Deficiency              : < 20 ng/ ml
Normal Range       : 20 – 30 ng/ml
Sufficiency             : 30 -100 ng/ml
Toxicity                   : >100 ng/ml

Treatment – Vitamin D deficiency is generally treated by prescribing Vitamin D supplements and again re-checking after a few weeks for the results. If you feel you might be deficient in Vitamin D visit a doctor to treat it. Taking vitamin D deficiency lightly only because it is very common, is not advisable.

 

RRMCH one of the leading private medical college and hospital in Bangalore